‫ CORRECTING AND REPLACING – يسر دار فايدي أن تعلن عن عقد أول دورة تعريفية في العالم في مجال أحجار الياقوت في دبي في الفترة من 27 أبريل حتى 4 مايو ،

MONACO CITY, MONACO / ACCESSWIRE / April 13, 2023

يسر دار فايدي أن تعلن عن عقد أول دورة تعريفية في العالم في مجال أحجار الياقوت في دبي في الفترة من 27 أبريل حتى 4 مايو ، وذلك باستضافة فنسنت بارديو ، عالم الأحجار الكريمة المشهور عالميًا الذي زار تقريبًا جميع مناجم الأحجار الكريمة حول العالم ، و رافي لونيا ، المدير الإبداعي في دار فايدي ، وهي الجيل الرابع لنشاط العائلة المتخصص في أجود أنواع أحجار الياقوت البورمي. وقامت ألينا برنارد ، وهي مؤسس شركة لإدارة العلامات التجارية والعلاقات العامة والحائزة على جوائز في لندن ، بإعداد الدورة التمهيدية وتنظيمها واستضافتها.

ستُعقد الدورة التمهيدية عن الياقوت في لانا ريزيدنس ، مجموعة دورتشستر وون بالم جميرا ، مجموعة دورتشستر ، دبي التي طورتها مجموعة أمنيات العقارية ، في الفترة من 27 أبريل – 30 أبريل 2023.

وإضافةً إلى ذلك ، يُعقد يومًا إعلاميًا في 2 مايو 2023 في واحدٍ من أكثر الأماكن أناقة في دبي.

ستتيح الجلسة التي تستغرق ساعتين الفرصة لفهم جودة الأحجار الكريمة الجيدة من خلال عدة عوامل مثل المنشأ واللون ودرجة النقاء وطريقة القطع ، وذلك باستخدام نماذج من الياقوت الحقيقي القيِّم. وستكتسب معرفة أعمق حول الأهمية التاريخية والثقافية لحجر الياقوت بالإضافة إلى مقدمة موجزة عن كيفية جعل أحجار الياقوت استثمارًا بديلاً محتملاً.

تقتصر الدورات المنعقدة على أصحاب الثروات المالية الضخمة ولا يتم الدخول إليها إلا من خلال دعوات. إنها فرصة نادرة وامتياز خاص للتعرف على حجر الياقوت ، المعروف باسم ملك الأحجار الكريمة ، وذلك من خلال جلسة تفاعلية مع متخصصين مثل فنسنت ورافي ، الذين كرسوا حياتهم لهذا النوع من الأحجار.

بيانات الاتصال

مسؤول الاتصال: ألينا برنارد ( مسؤول العلاقات العامة والجهة المنظمة للدورة التمهيدية في دبي )

رقم التليفون: +447872968698

عنوان البريد الإلكتروني: alina@rustyleltd.com

رابط الموقع الإلكتروني: https://www.faidee.com

ALCO DEADLINE NOTICE: ROSEN, TRUSTED INVESTOR COUNSEL, Encourages Alico, Inc. Investors to Secure Counsel Before Important April 18 Deadline in Securities Class Action – ALCO

NEW YORK, April 13, 2023 (GLOBE NEWSWIRE) — WHY: Rosen Law Firm, a global investor rights law firm, reminds purchasers of securities of Alico, Inc. (NASDAQ: ALCO) between February 4, 2021 and December 13, 2022, both dates inclusive (the “Class Period”), of the important April 18, 2023 lead plaintiff deadline.

SO WHAT: If you purchased Alico securities during the Class Period you may be entitled to compensation without payment of any out of pocket fees or costs through a contingency fee arrangement.

WHAT TO DO NEXT: To join the Alico class action, go to https://rosenlegal.com/submit-form/?case_id=13493 or call Phillip Kim, Esq. toll-free at 866-767-3653 or email pkim@rosenlegal.com or cases@rosenlegal.com for information on the class action. A class action lawsuit has already been filed. If you wish to serve as lead plaintiff, you must move the Court no later than April 18, 2023. A lead plaintiff is a representative party acting on behalf of other class members in directing the litigation.

WHY ROSEN LAW: We encourage investors to select qualified counsel with a track record of success in leadership roles. Often, firms issuing notices do not have comparable experience, resources or any meaningful peer recognition. Many of these firms do not actually handle securities class actions, but are merely middlemen that refer clients or partner with law firms that actually litigate the cases. Be wise in selecting counsel. The Rosen Law Firm represents investors throughout the globe, concentrating its practice in securities class actions and shareholder derivative litigation. Rosen Law Firm has achieved the largest ever securities class action settlement against a Chinese Company. Rosen Law Firm was Ranked No. 1 by ISS Securities Class Action Services for number of securities class action settlements in 2017. The firm has been ranked in the top 4 each year since 2013 and has recovered hundreds of millions of dollars for investors. In 2019 alone the firm secured over $438 million for investors. In 2020, founding partner Laurence Rosen was named by law360 as a Titan of Plaintiffs’ Bar. Many of the firm’s attorneys have been recognized by Lawdragon and Super Lawyers.

DETAILS OF THE CASE: According to the lawsuit, defendants throughout the Class Period made false and/or misleading statements and/or failed to disclose that: (1) Alico had deficient disclosure controls and procedures and internal control over financial reporting; (2) as a result, the Company had improperly calculated Alico’s deferred tax liabilities over a multi-year period; (3) accordingly, the Company would likely be required to restate one or more of its previously issued financial statements; (4) the foregoing would impede the timely completion of the audit of the Company’s financial results in advance of its year-end earnings call; and (5) as a result, the Company’s public statements were materially false and misleading at all relevant times. When the true details entered the market, the lawsuit claims that investors suffered damages.

To join the Alico class action, go to https://rosenlegal.com/submit-form/?case_id=13493 or call Phillip Kim, Esq. toll-free at 866-767-3653 or email pkim@rosenlegal.com or cases@rosenlegal.com for information on the class action.

No Class Has Been Certified. Until a class is certified, you are not represented by counsel unless you retain one. You may select counsel of your choice. You may also remain an absent class member and do nothing at this point. An investor’s ability to share in any potential future recovery is not dependent upon serving as lead plaintiff.

Follow us for updates on LinkedIn: https://www.linkedin.com/company/the-rosen-law-firm, on Twitter: https://twitter.com/rosen_firm or on Facebook: https://www.facebook.com/rosenlawfirm/.

Attorney Advertising. Prior results do not guarantee a similar outcome.

——————————

Contact Information:

Laurence Rosen, Esq.
Phillip Kim, Esq.
The Rosen Law Firm, P.A.
275 Madison Avenue, 40th Floor
New York, NY 10016
Tel: (212) 686-1060
Toll Free: (866) 767-3653
Fax: (212) 202-3827
lrosen@rosenlegal.com
pkim@rosenlegal.com
cases@rosenlegal.com
www.rosenlegal.com

GlobeNewswire Distribution ID 8807528

CORRECTING AND REPLACING: Faidee Is Proud To Announce the World’s First Ruby Masterclass in Dubai From 27 April Till 4 May

MONACO CITY, MONACO / ACCESSWIRE / April 13, 2023 / Faidee is proud to announce the world’s first Ruby Masterclass in Dubai from 27 April till 4 May, hosted by world renowned field gemologist who has visiting almost all gemstone mines in the world, Vincent Pardieu, and Ravi Lunia, Creative Director at Faidee, a fourth-generation family business specializing in the finest Burmese rubies. Brought by, organised & hosted by Alina Burnard, founder of an award winning PR & Brand management company in London.

The Ruby Masterclass will be held at The Lana Residences, Dorchester Collection, Dubai, and One at Palm Jumeirah, Dorchester Collection, Dubai, by OMNIYAT from April 27 – April 30, 2023.

In addition a special press day will be held on May 2nd 2023 in one of the most stylish place in Dubai.

Using real and valuable rubies as samples, the two hour session will give the chance to understand the quality of a good gem through factors such as origin, color, clarity and cut. You will gain deeper knowledge about the historical and cultural relevance of rubies as well as a brief introduction on how ruby can be a potential alternative investment.

The classes are exclusive for UHNWI and accessed by invitation only. It is a rare chance and privilege to learn about the ruby, also known as the King of Gemstones, through an interactive session with such specialists as Vincent and Ravi, as they have devoted their lives to the stone.

About Company Section

Faidee was founded in the early 1900s by Roop Chand Lunia. As a gemstone dealer, he was known for his collection of rare and exceptional stones. His ability to foresee the potential of a rough and unlock its hidden beauty was incomparable. His expertise made him, incontrovertibly, one of the most dynamic gemstone dealers of his time, earning him the title of ‘King of the Burmese Ruby. Being the only company to deal exclusively in burmese rubies, faidee stands at the pinnacle of the industry, with the most scintillating collection of rubies in the world.

Contact Information:
Contact Names: Alina Burnard (PR & organiser of the Masterclass in Dubai)
Phone Number: +447872968698
Email Address: alina@rustyleltd.com
Website Link: https://www.faidee.com/

SOURCE: Faidee

ROSEN,A LONGSTANDING LAW FIRM, Encourages Amgen Inc. Investors with Losses to Secure Counsel Before Important Deadline in Securities Class Action – AMGN

NEW YORK, April 13, 2023 (GLOBE NEWSWIRE) —

WHY: Rosen Law Firm, a global investor rights law firm, reminds purchasers of securities of Amgen Inc. (NASDAQ: AMGN) between July 29, 2020 and April 27, 2022, both dates inclusive (the “Class Period”), of the important May 12, 2023.

SO WHAT: If you purchased Amgen securities during the Class Period you may be entitled to compensation without payment of any out of pocket fees or costs through a contingency fee arrangement.

WHAT TO DO NEXT: To join the Amgen class action, go to https://rosenlegal.com/submit-form/?case_id=13114 or call Phillip Kim, Esq. toll-free at 866-767-3653 or email pkim@rosenlegal.com or cases@rosenlegal.com for information on the class action. A class action lawsuit has already been filed. If you wish to serve as lead plaintiff, you must move the Court no later than May 12, 2023. A lead plaintiff is a representative party acting on behalf of other class members in directing the litigation.

WHY ROSEN LAW: We encourage investors to select qualified counsel with a track record of success in leadership roles. Often, firms issuing notices do not have comparable experience, resources or any meaningful peer recognition. Many of these firms do not actually handle securities class actions, but are merely middlemen that refer clients or partner with law firms that actually litigate the cases. Be wise in selecting counsel. The Rosen Law Firm represents investors throughout the globe, concentrating its practice in securities class actions and shareholder derivative litigation. Rosen Law Firm has achieved the largest ever securities class action settlement against a Chinese Company. Rosen Law Firm was Ranked No. 1 by ISS Securities Class Action Services for number of securities class action settlements in 2017. The firm has been ranked in the top 4 each year since 2013 and has recovered hundreds of millions of dollars for investors. In 2019 alone the firm secured over $438 million for investors. In 2020, founding partner Laurence Rosen was named by law360 as a Titan of Plaintiffs’ Bar. Many of the firm’s attorneys have been recognized by Lawdragon and Super Lawyers.

DETAILS OF THE CASE: According to the lawsuit, defendants throughout the Class Period made false and/or misleading statements and/or failed to disclose that: (1) the U.S. government claimed Amgen owed more than $3 billion in back taxes for tax years 2010, 2011, and 2012; (2) the U.S. government claimed Amgen owed more than $5 billion in back taxes for tax years 2013, 2014, and 2015; (3) the U.S. government would likely claim Amgen owed materially more to the U.S. government than investors had been led to believe for subsequent tax years for which the Company had used the same profit allocation treatment between its U.S. and Puerto Rico operations; (4) Amgen had not taken sufficient accruals to account for its outstanding tax liabilities; (5) Amgen had failed to comply with ASC 450 and other rules and regulations regarding the preparation of its periodic SEC filings; and (6) Amgen’s refusal to pay taxes claimed by the U.S. government exposed the Company to a substantial risk of severe financial penalties imposed by the IRS. When the true details entered the market, the lawsuit claims that investors suffered damages.

To join the Amgen class action, go to https://rosenlegal.com/submit-form/?case_id=13114 or call Phillip Kim, Esq. toll-free at 866-767-3653 or email pkim@rosenlegal.com or cases@rosenlegal.com for information on the class action.

No Class Has Been Certified. Until a class is certified, you are not represented by counsel unless you retain one. You may select counsel of your choice. You may also remain an absent class member and do nothing at this point. An investor’s ability to share in any potential future recovery is not dependent upon serving as lead plaintiff.

Follow us for updates on LinkedIn: https://www.linkedin.com/company/the-rosen-law-firm, on Twitter: https://twitter.com/rosen_firm or on Facebook: https://www.facebook.com/rosenlawfirm/.

Attorney Advertising. Prior results do not guarantee a similar outcome.

——————————

Contact Information:

Laurence Rosen, Esq.
Phillip Kim, Esq.
The Rosen Law Firm, P.A.
275 Madison Avenue, 40th Floor
New York, NY 10016
Tel: (212) 686-1060
Toll Free: (866) 767-3653
Fax: (212) 202-3827
lrosen@rosenlegal.com
pkim@rosenlegal.com
cases@rosenlegal.com
www.rosenlegal.com

GlobeNewswire Distribution ID 8807554

ROSEN, A LEADING NATIONAL FIRM, Encourages BlockFi Interest Account Investors with Losses to Secure Counsel Before Important Deadline in Securities Class Action Against Zac Prince, Flori Marquez, Amit Cheela, David Olsson, and Samia Bayou

NEW YORK, April 13, 2023 (GLOBE NEWSWIRE) — WHY: Rosen Law Firm, a global investor rights law firm, reminds investors in BlockFi Interest Accounts (“BIAs”) between March 4, 2019 and November 28, 2022, inclusive (the “Class Period”), against Zac Prince, Flori Marquez, Amit Cheela, David Olsson, and Samia Bayou (together, “Defendants”), of the important May 1, 2023 lead plaintiff deadline.

SO WHAT: If you invested in BlockFi Interest Accounts (“BIAs”) during the Class Period you may be entitled to compensation without payment of any out of pocket fees or costs through a contingency fee arrangement.

WHAT TO DO NEXT: To join the BlockFi class action, go to https://rosenlegal.com/submit-form/?case_id=12656 or call Phillip Kim, Esq. toll-free at 866-767-3653 or email pkim@rosenlegal.com or cases@rosenlegal.com for information on the class action. A class action lawsuit has already been filed. If you wish to serve as lead plaintiff, you must move the Court no later than May 1, 2023. A lead plaintiff is a representative party acting on behalf of other class members in directing the litigation.

WHY ROSEN LAW: We encourage investors to select qualified counsel with a track record of success in leadership roles. Often, firms issuing notices do not have comparable experience, resources or any meaningful peer recognition. Many of these firms do not actually litigate securities class actions, but are merely middlemen that refer clients or partner with law firms that actually litigate the cases. Be wise in selecting counsel. The Rosen Law Firm represents investors throughout the globe, concentrating its practice in securities class actions and shareholder derivative litigation. Rosen Law Firm has achieved the largest ever securities class action settlement against a Chinese Company. Rosen Law Firm was Ranked No. 1 by ISS Securities Class Action Services for number of securities class action settlements in 2017. The firm has been ranked in the top 4 each year since 2013 and has recovered hundreds of millions of dollars for investors. In 2019 alone the firm secured over $438 million for investors. In 2020, founding partner Laurence Rosen was named by law360 as a Titan of Plaintiffs’ Bar. Many of the firm’s attorneys have been recognized by Lawdragon and Super Lawyers.

DETAILS OF THE CASE: According to the lawsuit, the Defendants made false and misleading statements to promote BlockFi Interest Accounts (“BIAs”), including that BIAs were a secure method of collecting interest. In addition, the Complaint alleges, among other things, that the defendants omitted and concealed material information concerning the risks associated with BIAs, including through BlockFi’s exposure to FTX Trading, Ltd. (“FTX”) and Sam Bankman-Fried’s trading firm Alameda Research (“Alameda”), both of which collapsed in the wake of revelations that FTX and Alameda were engaging in fraud on a massive scale. In the wake of the FTX collapse, the lawsuit alleges that BlockFi froze withdrawals in BIAs, harming BIA investors. Further, investors in BIAs were not aware of conflicts of interest and self-dealing between BlockFi and other entities, such as Gemini Trust LLC, controlled by Tyler and Cameron Winklevoss. The Complaint further alleges BlockFi and the Individual Defendants engaged in the unlawful offer and sale of securities in violation of Sections 5, 11, 12(a)(2), and 15 of the Securities Act of 1933 by selling BIAs to investors. The lawsuit also alleges claims for violation of Section 10(b) and 20 of the Securities Exchange Act of 1934 and Massachusetts General Law Chapter 110A.

To join the BlockFi class action, go to https://rosenlegal.com/submit-form/?case_id=12656 or call Phillip Kim, Esq. toll-free at 866-767-3653 or email pkim@rosenlegal.com or cases@rosenlegal.com for information on the class action.

No Class Has Been Certified. Until a class is certified, you are not represented by counsel unless you retain one. You may select counsel of your choice. You may also remain an absent class member and do nothing at this point. An investor’s ability to share in any potential future recovery is not dependent upon serving as lead plaintiff.

Follow us for updates on LinkedIn: https://www.linkedin.com/company/the-rosen-law-firm, on Twitter: https://twitter.com/rosen_firm or on Facebook: https://www.facebook.com/rosenlawfirm/.

Attorney Advertising. Prior results do not guarantee a similar outcome.

Contact Information:

Laurence Rosen, Esq.
Phillip Kim, Esq.
The Rosen Law Firm, P.A.
275 Madison Avenue, 40th Floor
New York, NY 10016
Tel: (212) 686-1060
Toll Free: (866) 767-3653
Fax: (212) 202-3827
lrosen@rosenlegal.com
pkim@rosenlegal.com
cases@rosenlegal.com
www.rosenlegal.com

GlobeNewswire Distribution ID 8807527

Pioneering a More Collaborative Future for Manufacturing: weavix is Exhibiting at Hannover Messe 2023

WICHITA, KS / ACCESSWIRE / April 13, 2023 / weavix™ is set to showcase the latest innovations to its communications and productivity platform on April 17-21 at Hannover Messe 2023, a leading international conference specializing in industrial transformation for manufacturers.

Related Images

weavix and Microsoft Teams integration
walt smart radio showing the integration with Microsoft Teams

weavix™ will highlight its integration with Microsoft Azure Private 5G Core, which enables its platform to deliver enterprise-vital solutions, thus supporting the Internet of Workers platform with integration with Azure services, enhanced security, low latency and dependability.

Following the company’s collaboration with Microsoft at Mobile World Congress earlier this year, weavix™ is rolling out its integration with Microsoft Teams®. The goal is to leverage the connectivity and solutions provided by Azure Private 5G Core to allow for collaboration between office and frontline workers and address efficiency issues more directly.

“Microsoft has a long and tremendous history with communication technology for office workers,” said Ben Burrus, Chief Product Officer at weavix™. “The interoperability between Teams® and weavix™ helps to break down the overt communication barriers that exist between the two distinct groups of workers and, in turn, makes the other 80% of the workforce more accessible. This pairing allows for a seamless and direct route for office workers to communicate using audio and video to frontline workers via the walt™ smart radio.”

“Modernizing and empowering frontline workers represent a big opportunity in the evolution and advancement of the manufacturing industry,” said Shriraj Gaglani, VP of Product Development, Microsoft. “Manufacturing personnel must be able to effectively communicate on-site and off to continue producing at optimal levels, and we are pleased to see weavix™ growing their portfolio of solutions using Azure private MEC and adding Microsoft Teams® integration to address this opportunity and unmet need.”

At the conference, manufacturing professionals and attendees can operate and test the walt™ smart radio and experience a complete demonstration of the platform’s communication and productivity solutions.

Hannover Messe is an international hotspot for the latest in technological advances for industry, drawing in an estimated 200,000 manufacturing professionals, exhibitors, decision-makers and industrial pioneers.

weavix™ is exhibiting alongside Microsoft’s other co-innovation partners in Hall 17 as part of the Intelligent Factory sector. To meet with weavix™ at Hannover Messe 2023 in Hannover, Germany, schedule a time here.

About weavix™

weavix™, the Internet of Workers™ platform, revolutionizes frontline communication and productivity on a global scale. Since its founding, weavix™ has shaped the future of work by introducing innovative methods to better connect and empower the frontline workforce, like Enterprise-Vital Push-to-Three (EVPT3) communication. weavix™ transforms enterprise by providing data-driven insights into facilities and teams to maximize productivity and achieve breakthrough results. weavix™ is the single source of truth for both workers and executives. Our mission is to empower workers around the world with disruptive technology. Visit https://weavix.com/ for more information.

Contact Information

Monica Poe
Marketing Director, weavix™
mpoe@weavix.com
3165195912

Justin Nickel
Chief Marketing Officer, weavix™
jnickel@weavix.com
3168662955 ext. 533

SOURCE: weavix

Russian aid plane arrives in Lattakia International Airport

A Russian plane carrying relief aid to the earthquake-affected people arrived in Lattakia International Airport on Thursday.

Director of Lattakia Airport, Eng. Ziyad al-Tawil told SANA reporter in a statement, that the Russian plane carries 17 tons of aid relief for the earthquake-affected people in the afflicted areas.

Source: Syrian Arab News Agency

Syria, Saudi Arabia welcome the resumption of consular services and air flights between the two countries

Syria and Saudi Arabia welcomed the resumption of consular services and air flights between the two countries, affirming the necessity of boosting security and combating terrorism with all its forms and organizations.

“In the framework of Saudi Arabia’s commitment to the Arab causes, and to boost the interests of the Arab countries and people, and in response to an invitation by his highness, Prince Faisal bin Farhan Al Saud, the Foreign Minister of Saudi Arabia, Syrian Foreign Minister, Fayssal Mikdad visited the Kingdom today,” A joint press statement said at the conclusion of the visit of Mr. Mikdad to Saudi Arabia.

The statement added that a session of talks was held between the two sides, during which they discussed the efforts exerted to realize a political solution to the crisis in Syria that keeps its security, stability, Arab and Islamic identify and territorial integrity in the interest of the Syrian people.

The two sides stressed the importance of solving the humanitarian difficulties, providing a suitable environment to deliver aid to all regions in Syria, availing the proper conditions for the return of Syrian refugees and the displaced to their areas, ending their suffering and taking more procedures that help stabilize the situation all over Syrian territories, the statement said.

It added that the two sides also affirmed the necessity of boosting security, combating terrorism with all its forms and boosting cooperation regarding war on smuggling drugs and trafficking in it, and the need to support the Syrian State’s institutions to establish its control on its territories to end the presence of the armed militias and the foreign interventions in the Syrian domestic affair.

“The two sides discussed the steps needed to achieve a comprehensive political settlement in Syria that ends all its repercussions, realizes the national reconciliation and helps Syria’s return to its Arab surrounding and resume its normal role in the Arab nation,” the statement said.

At the conclusion of the statement, the two sides welcomed the beginning of procedures to resume the consular services and aerial flights between the two countries.

Mikdad expressed Syria’s appreciation to the efforts exerted by Saudi Arabia to end the crisis in Syria and the humanitarian aid it provides to the earthquake- affected people in Syria.

Source: Syrian Arab News Agency

KSrelief Distributes 63 Tons of Food Baskets in Hadibu and Qulensya Districts in Socotra Governorate

The King Salman Humanitarian Aid and Relief Center (KSrelief) distributed 63 tons and 617 kilograms of food baskets on Monday in Hadibu and Qulensya districts in Socotra governorate, Yemen, benefiting 8,316 people.

The aid is part of relief and humanitarian projects that the Kingdom of Saudi Arabia implements through its humanitarian arm, KSrelief, in Yamen.

Source: Saudi Press Agency

President of Nigeria Arrives in Jeddah

President Muhammadu Buhari of the Federal Republic of Nigeria arrived in Jeddah today.

Upon arrival, the Nigerian president was received by Prince Bader bin Sultan bin Abdulaziz, the Deputy Governor of Makkah region, and several officials.

Source: Saudi Press Agency

KSrelief Delivers 3,000 Tons of Dates to WFP for Distribution in Six Yemeni Governorates

King Salman Humanitarian Aid and Relief Center (KSrelief) has delivered 3,000 metric tons of dates to the U.N. World Food Program (WFP), to be distributed to 1.8 million people in six Yemeni governorates.

Director of the World Food Office in Aden, Mark Jordan, stressed the importance of the aid provided by the Kingdom through KSrelief, which will contribute to meeting the needs of the needy and affected people in Yemen.

He said the distribution process is carried out according to a precise mechanism targeting those who are eligible.

This aid comes within the humanitarian and relief projects provided by the Kingdom, represented by the KSrelief, to provide food security for the Yemeni people and improve their living conditions in all fields.

Source: Saudi Press Agency

Study Reveals Cancer’s ‘infinite’ Ability to Evolve

An unprecedented analysis of how cancers grow has revealed an “almost infinite” ability of tumours to evolve and survive, say scientists.

The results of tracking lung cancers for nine years left the research team “surprised” and “in awe” at the formidable force they were up against.

They have concluded we need more focus on prevention, with a “universal” cure unlikely any time soon.

Cancer Research UK said early detection of cancer was vitally important, BBC news reported.

The study – entitled TracerX – provides the most in-depth analysis of how cancers evolve and what causes them to spread.

Cancers change and evolve over time – they are not fixed and immutable. They can become more aggressive: better at evading the immune system and able to spread around the body.

A tumour starts as a single, corrupted cell, but becomes a mixture of millions of cells that have all mutated in slightly different ways.

TracerX tracked that diversity and how it changes over time inside lung cancer patients and say the results would apply across different types of cancer.

“That has never been done before at this scale,” said Prof Charles Swanton, from the Francis Crick Institute and University College London.

More than 400 people – treated at 13 hospitals in the UK – had biopsies taken from different parts of their lung cancer as the disease progressed.

“It has surprised me how adaptable tumours can be,” Prof Swanton told me.

“I don’t want to sound too depressing about this, but I think – given the almost infinite possibilities in which a tumour can evolve, and the very large number of cells in a late-stage tumour, which could be several hundred billion cells – then achieving cures in all patients with late-stage disease is a formidable task.”

Prof Swanton said: “I don’t think we’re going to be able to come up with universal cures.

“If we want to make the biggest impact we need to focus on prevention, early detection and early detection of relapse,” he added.

Obesity, smoking, alcohol and poor diet all increase the risk of some cancers. Tackling inflammation in the body is also being seen as a way of preventing cancer. Inflammation is the likely explanation for air pollution causing lung cancers and inflammatory bowel disease increasing the risk of colon cancer.

The evolutionary analysis has been published across seven separate studies in the journals Nature and Nature Medicine.

Source: Oman News Agency